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Insulin

Diabetologia November 2016: These results support the causal role of insulin in the pathogenesis of CHD. Efficient treatment and prevention of insulin resistance is essential to prevent future CHD events.

Diabetic Medicine June 2002: Insulin resistance in non-diabetic subjects is associated with increased incidence of myocardial infarction and death

Diabetes Care Feb 2009: This modeling exercise has important practical implications. It addresses the relative importance of well-known variables in the genesis of CAD and suggests areas that should be the focus of research and treatment. More specifically, our results indicate that insulin resistance itself has a profound effect on CAD—greater than previously realized. In fact, it is likely the most important single determinant of CAD

BMJ 2016: This study demonstrates that strict adherence to dietary intervention with the high protein diet is possible and results in remission of pre-diabetes to normal glucose tolerance.

Clinical Pharmacist Jul 2017: Malhotra, Demasi, Lustig: The cholesterol and calorie hypotheses are both dead — it is time to focus on the real culprit: insulin resistance.

"hyperinsulinemia is at the very centre of all the problems of PCOS (Polycystic Ovarian Syndrome"

Cancer epidemiology, biomarkers & prevention 2014: Risk of Breast Cancer Recurrence Associated with Carbohydrate Intake and Tissue Expression of IGF-1 Receptor. Among women whose tumor tissue is positive for the IGF-1 receptor, reducing carbohydrate intake after diagnosis could reduce the risk of breast cancer recurrence.

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